BackgroundMelanoma has the highest mortality rate among all the types of skin cancer.In melanoma, M2-like tumor-associated macrophages (TAMs) are associated with the invasiveness of tumor cells and a poor prognosis.Hence, the depletion or reduction of M2-TAMs is a therapeutic strategy for the inhibition of tumor progression.The aim of this study wa

Abstract People with mental illnesses are overrepresented in criminal legal systems internationally, making addressing mental health among this population a global public health concern.Across the world, community supervision agencies (i.e., probation and parole) have implemented a variety of innovative and evidence-informed approaches to improve o

In the present paper, partial cavitation over various head-forms was studied numerically to predict the shape of the cavity.Navier-Stokes equations in addition to an advection equation for vapor volume fraction were solved.Mass transfer between the phases was modeled by a sink term in vapor equation in the numerical analysis for different geometrie

Neutrophil extracellular traps (NETs) recently emerged as a newly recognized contributor to venous and arterial thrombosis.These strands of DNA, extruded by activated or dying neutrophils, decorated with various protein mediators, become solid-state reactors that can localize SOCKS at the critical interface of blood with the intimal surface of dise